糖尿病、非酒精性脂肪性肝病、肥胖及代谢性疾病的诊治

夏明锋，现任复旦大学附属中山医院内分泌科主治医师，中华医学会糖尿病分会流行病学组委员。毕业于复旦大学上海医学院八年制临床医学专业，医学博士，曾至美国耶鲁大学交流学习。擅长糖尿病、非酒精性脂肪性肝病、肥胖及代谢性疾病的诊治，在国际上首创建立标准化超声定量肝脏脂肪含量方法，曾获“上海市住院医师规范化培训优秀住院医师”、“上海市高校优秀毕业生”、“全国医学生临床技能大赛三等奖”。 科研方面作为课题负责人，承担国家自然科学基金、上海市卫计委、中山医院青年基金课题。迄今已第一作者发表论文16篇，其中SCI论文12篇，影响因子43.8分，他引109次，参与完成注册临床研究2项，以第三完成人身份获得国家发明专利2项，曾获得上海市医学科技进步二等奖和推广奖以及中山医院第二届“科技新星”称号。 发表文章： 1. Xia MF, Bian H, Zhu XP, Yan HM, Chang XX, Zhang LS, Lin HD, Hu XQ, Gao X. Serum folic acid levels are associated with the presence and severity of liver steatosis in Chinese adults. Clin Nutr. 2017 Jun 28. pii: S0261-5614(17)30232-7. 2. Xia MF, Chen Y, Lin HD, Ma H, Li XM, Aleteng Q, Li Q, Wang D, Hu Y, Pan BS, Li XJ, Li XY, Gao X. A indicator of visceral adipose dysfunction to evaluate metabolic health in adult Chinese.Sci Rep. 2016;6:38214. 3. Xia MF, Lin HD, Yan HM, Bian H, Chang XX, Zhang LS, He WY, Gao X. The association of liver fat content and serum alanine aminotransferase with bone mineral density in middle-aged and elderly Chinese men and postmenopausal women. J Transl Med. 2016;14(1):11. 4. Xia MF, Ling Y, Bian H, Lin HD, Yan HM, Chang XX, Li XM, Ma H, Wang D, Zhang LS, Wang SS, Wu BJ, He WY, Zhao NQ, Gao X. I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders. Aliment Pharmacol Ther. 2016;43(5): 631-42. 5. Xia MF, Yki-J??rvinen H，Bian H, Lin HD, Yan HM, Chang XX, Zhou Y, Gao X. Influence of ethnicity on the accuracy of non-invasive scores predicting non-alcoholic fatty liver disease. PLOS ONE 2016(Accepted). 6. Wang D, Lin H, Xia M (共同第一), Aleteng Q, Li X, Ma H, Pan B, Gao J, Gao X. Vitamin D Levels Are Inversely Associated with Liver Fat Content and Risk of Non-Alcoholic Fatty Liver Disease in a Chinese Middle-Aged and Elderly Population: The Shanghai Changfeng Study.PLoS One. 2016;11(6):e0157515. 7. Yan HM, Xia MF（共同第一）, Wang Y, Chang XX, Yao XZ, Rao SX, Zeng MS, Tu YF, Feng R, Jia WP, Liu J, Deng W, Jiang JD, Gao X. Efficacy of Berberine in Patients with Non-Alcoholic Fatty Liver Disease. PLoS One. 2015;10(8):e0134172. 8. Xia MF, Bian H, Yan HM, Lin HD, Chang XX, Li XM, Ma H, He WY, Zhao NQ, Xia P, Gao X. Assessment of liver fat content using quantitative ultrasonography to evaluate risks for metabolic diseases.Obesity (Silver Spring). 2015;23(9):1929-37. 9. Xia MF, Lin HD, Li XM, Yan HM, Bian H, Chang XX, He WY, Jeekel J, Hofman A,Gao X* (Corresponding author). Renal function- dependent association of serum uric acid with metabolic syndrome and hepatic fat content in a middle-aged and elderly Chinese population. Clin Exp Pharmacol Physiol. 2012;39(11):930-7. 10.Xia MF, Yan HM, He WY, Li XM, Li CL, Yao XZ, Li RK, Zeng MS, Gao X*(Corresponding author). Standardized Ultrasound Hepatic/Renal Ratio and Hepatic Attenuation Rate to Quantify Liver Fat Content: An Improvement Method. Obesity (Silver Spring). 2012 ;20(2):444-52. 11.Xia MF, Yan HM, Lin HD, Bian H, Pan BS, Yao XZ, Li RK, Zeng MS, Gao X*(Corresponding author). Elevation of liver enzymes within the normal limits and metabolic syndrome. Clin Exp Pharmacol Physiol. 2011 Jun;38(6):373-9. 12.Xia M, Bian M, Yu Q, Liu J, Huang Y, Jin X, Lu S, Yu M, Huang F. Cold water stress attenuates dopaminergic neurotoxicity induced by 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine in mice. Acta Biochim Biophys Sin (Shanghai). 2011;43(6):448-54.